- Domain
- Critical Technology · Hard Power
- Identifier
- factbase.org/cpg/C1R7JPV524
- Capabilities
- 5
Bounds. Holds biotechnology as national capacity; the health system that delivers care belongs to Human Capital, hospitals, laboratories and stockpiles to Strategic Infrastructure, biological defence to National Security, the industry's economic weight to the economic domains, and the governance of biology, biosafety and research oversight, to the governance domain. Dual-use capacity is recorded as capacity, with employment classified where it occurs.
The 5 capabilities
The capabilities compared
Papers and patent families, 2020–2024, with growth on the five years before and the leading nation in each.
| Capability | Papers | Growth | Research leader | Families | Growth | Patent leader |
|---|---|---|---|---|---|---|
| Genomics & Biological Data | 14.9k | +20% | China 20% | 87.9k | +57% | China 70% |
| Synthetic Biology & Genetic Engineering | 6.8k | +5% | China 20% | 135.1k | +64% | China 70% |
| Biomanufacturing | 2.4k | +42% | China 14% | 126.5k | +38% | China 67% |
| Nuclear Medicine & Radioisotope Technologies | 33.4k | +6% | United States 21% | 14.5k | +29% | China 51% |
| Advanced Therapeutics, Vaccines & Medical Countermeasures | 94.7k | +104% | United States 21% | 81.3k | +55% | China 47% |
Who publishes it
Papers by year for each capability, and the nations' shares of the group's papers, 2020–2024. A capability that shares a v0.0 topic with another counts it in both.
- 1United States20.5%31,245 papers
- 2China9.1%13,911 papers
- 3United Kingdom6.0%9,166 papers
- 4India4.8%7,241 papers
- 5Germany3.9%5,992 papers
- 6Italy3.3%4,952 papers
- 7Canada2.9%4,491 papers
- 8Australia2.7%4,131 papers
- 9France2.4%3,712 papers
- 10Japan2.4%3,691 papers
Who patents it
Patent families by priority year for each capability, and the origin nations' shares of the group's families, 2020–2024. A family in two capabilities' classes counts in both.
- 1China64.3%286,282 families
- 2United States16.0%71,206 families
- 3South Korea5.1%22,917 families
- 4Japan4.2%18,894 families
- 5Germany1.4%6,192 families
- 6United Kingdom1.1%4,750 families
- 7France0.9%3,892 families
- 8Switzerland0.8%3,624 families
- 9Canada0.6%2,756 families
- 10Taiwan0.5%2,309 families
Who makes it
The companies across the group's capabilities, the global leaders and the leading firms of every region.
203 companies in Biotechnology & Health Technologies, from 39 nations across 8 regions; the leading 25 below. Sorted by how experts see each company's global relevance in its strongest capability of the group, from very high to very low.
- Very high23 companies
- 1Very highProfessional & data servicesBostonUnited States2008–DNA
Largest horizontal cell-programming platform, running automated foundries that design and engineer organisms for pharma, agriculture and industrial customers.
In Synthetic Biology & Genetic Engineering
Very high relevance · Professional & data services · United States, Boston · founded 2008
- 2Very highEquipment & machinerySan DiegoUnited States19988,970ILMN
Dominant supplier of short-read sequencing-by-synthesis instruments (NovaSeq X, NextSeq, MiSeq) and the top international patent applicant in this capability.
In Genomics & Biological Data
Very high relevance · Equipment & machinery · United States, San Diego · founded 1998 · 8,970 staff
- 3Very highChemicals & gasesNew YorkUnited States184981kPFE
Co-developed and manufactured the Comirnaty mRNA COVID-19 vaccine with BioNTech, produces Paxlovid oral antiviral and the Prevnar and Abrysvo vaccine franchises.
In Advanced Therapeutics, Vaccines & Medical Countermeasures
Very high relevance · Chemicals & gases · United States, New York · founded 1849 · 81k staff
- 4Very highHardware & devicesErlangenGermany184772kSHL
Leading maker of SPECT and PET/CT scanners (Biograph line) and, through PETNET Solutions, one of the largest PET radiopharmaceutical manufacturing and distribution networks; also owns Varian radiotherapy.
In Nuclear Medicine & Radioisotope Technologies
Very high relevance · Hardware & devices · Germany, Erlangen · founded 1847 · 72k staff
- 5Very highEquipment & machineryWalthamUnited States1956125kTMO
Largest supplier of bioprocess media, single-use systems and analytics, and through Patheon one of the largest biologics and viral-vector CDMOs.
In Biomanufacturing
Very high relevance · Equipment & machinery · United States, Waltham · founded 1956 · 125k staff
- 6Very highEquipment & machineryWashington, D.C.United States196963kDHR
Its Cytiva and Pall units are the leading suppliers of chromatography resins, filtration, bioreactors and turnkey modular biologics plants (KUBio).
In Biomanufacturing
Very high relevance · Equipment & machinery · United States, Washington, D.C. · founded 1969 · 63k staff
- 7Very highHardware & devicesChicagoUnited States202353kGEHC
Major supplier of PET/CT, SPECT/CT and cyclotrons plus a Pharmaceutical Diagnostics unit making SPECT and PET tracers (e.g. DaTscan, Vizamyl) and owner of the MIM Software molecular-imaging suite.
In Nuclear Medicine & Radioisotope Technologies
Very high relevance · Hardware & devices · United States, Chicago · founded 2023 · 53k staff
- 8Very highMedicines & vaccinesCambridge, MassachusettsUnited States20105,800MRNA
mRNA platform company behind Spikevax (COVID-19) and mRESVIA (RSV), with a pipeline of mRNA vaccines for influenza, CMV and individualized cancer vaccines.
In Advanced Therapeutics, Vaccines & Medical Countermeasures
Very high relevance · Medicines & vaccines · United States, Cambridge, Massachusetts · founded 2010 · 5,800 staff
- 9Very highProfessional & data servicesShenzhenChina1999–Private
China's genomics champion; its affiliate MGI Tech (SSE 688114) makes DNBSEQ sequencers that compete with Illumina, and BGI Genomics (SZSE 300676) is one of the world's largest sequencing service providers.
In Genomics & Biological Data
Very high relevance · Professional & data services · China, Shenzhen · founded 1999
- 10Very highContract manufacturingBaselSwitzerland189718kLONN
World's largest contract development and manufacturing organisation for biologics, cell and gene therapies, with mammalian and microbial capacity across Europe, US and Asia.
In Biomanufacturing
Very high relevance · Contract manufacturing · Switzerland, Basel · founded 1897 · 18k staff
- 11Very highMedicines & vaccinesRahway, New JerseyUnited States189175kMRK
Major vaccine maker (Gardasil, Capvaxive, Ervebo Ebola vaccine) and developer of antivirals (Lagevrio) and novel antibiotics.
In Advanced Therapeutics, Vaccines & Medical Countermeasures
Very high relevance · Medicines & vaccines · United States, Rahway, New Jersey · founded 1891 · 75k staff
- 12Very highMedicines & vaccinesBaselSwitzerland199676kNOVN
Global leader in radioligand therapy with Lutathera and Pluvicto (Lu-177), produced by its Advanced Accelerator Applications unit across dedicated radiopharmaceutical plants.
In Nuclear Medicine & Radioisotope Technologies
Very high relevance · Medicines & vaccines · Switzerland, Basel · founded 1996 · 76k staff
- 13Very highChemicals & gasesSouth San FranciscoUnited States2013–TWST
Leading high-throughput silicon-based DNA synthesis provider supplying synthetic genes, oligo pools and libraries to synthetic biologists.
In Synthetic Biology & Genetic Engineering
Very high relevance · Chemicals & gases · United States, South San Francisco · founded 2013
- 14Very highAdvanced materialsParisFrance2017–Private
One of the world's largest nuclear medicine companies, a top supplier of Mo-99/Tc-99m generators, I-131 and SPECT/PET radiopharmaceuticals, formed from Mallinckrodt Nuclear Medicine and IBA Molecular.
In Nuclear Medicine & Radioisotope Technologies
Very high relevance · Advanced materials · France, Paris · founded 2017
- 15Very highResearch & IPLondonUnited Kingdom200069kGSK
One of the world's largest vaccine businesses (Shingrix, Arexvy, Bexsero, pandemic adjuvant AS03) and developer of novel antibiotics such as gepotidacin.
In Advanced Therapeutics, Vaccines & Medical Countermeasures
Very high relevance · Research & IP · United Kingdom, London · founded 2000 · 69k staff
- 16Very highEquipment & machineryOxfordUnited Kingdom2005–ONT
Developer of nanopore long-read, real-time sequencers (MinION, GridION, PromethION) used from field surveillance to population genomics.
In Genomics & Biological Data
Very high relevance · Equipment & machinery · United Kingdom, Oxford · founded 2005
- 17Very highContract manufacturingIncheonSouth Korea2011–207940
Operates the world's largest single-site biologics manufacturing capacity at Songdo (over 780,000 L across Plants 1-5).
In Biomanufacturing
Very high relevance · Contract manufacturing · South Korea, Incheon · founded 2011
- 18Very highChemicals & gasesBagsværdDenmark2024–NSIS B
World's largest industrial enzyme and microbial solutions company (merger of Novozymes and Chr. Hansen), engineering production strains and enzymes at global scale.
In Synthetic Biology & Genetic Engineering
Very high relevance · Chemicals & gases · Denmark, Bagsværd · founded 2024
- 19Very highMedicines & vaccinesParisFrance197383kSAN
Sanofi Pasteur is a top global vaccine producer (influenza, pediatric, meningitis) and co-developer of the Beyfortus RSV antibody, with mRNA capability from its Translate Bio acquisition.
In Advanced Therapeutics, Vaccines & Medical Countermeasures
Very high relevance · Medicines & vaccines · France, Paris · founded 1973 · 83k staff
- 20Very highResearch & IPZugSwitzerland2013–CRSP
Co-developer with Vertex of Casgevy, the first approved CRISPR-based gene-editing medicine (2023).
In Synthetic Biology & Genetic Engineering
Very high relevance · Research & IP · Switzerland, Zug · founded 2013
- 21Very highEquipment & machineryGöttingenGermany1870–SRT3
Sartorius Stedim Biotech is a leading maker of single-use bioreactors, filters, fluid management and cell culture media for biologics production.
In Biomanufacturing
Very high relevance · Equipment & machinery · Germany, Göttingen · founded 1870
- 22Very highMedicines & vaccinesMainzGermany20086,772BNTX
Invented the BNT162b2 mRNA COVID-19 vaccine, is developing mRNA cancer immunotherapies, and agreed to acquire CureVac in 2025.
In Advanced Therapeutics, Vaccines & Medical Countermeasures
Very high relevance · Medicines & vaccines · Germany, Mainz · founded 2008 · 6,772 staff
- 23Very highMedicines & vaccinesLeverkusenGermany1863–BAYN
Global leader in genetically engineered crop traits (ex-Monsanto) now pursuing gene-edited crops, and co-founder of the Joyn Bio microbial engineering venture with Ginkgo.
In Synthetic Biology & Genetic Engineering
Very high relevance · Medicines & vaccines · Germany, Leverkusen · founded 1863
- High2 companies
- 24HighAdvanced materialsBedfordUnited States1956–LNTH
Markets the leading PSMA PET agent Pylarify, TechneLite Tc-99m generators and cardiac imaging agents, and is building a radiotherapeutics pipeline.
In Nuclear Medicine & Radioisotope Technologies
High relevance · Advanced materials · United States, Bedford · founded 1956
- 25HighEquipment & machineryMenlo ParkUnited States2000–PACB
Maker of HiFi long-read SMRT sequencers (Revio, Vega) and the Onso short-read system, widely used for reference genomes and population programmes.
In Genomics & Biological Data
High relevance · Equipment & machinery · United States, Menlo Park · founded 2000